← Mechanisms of action
HAO1
SINGLE PROTEINHomo sapiens
Preferred name: Hydroxyacid oxidase 1 ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| lumasiran (Oxlumo) | Antagonist | approved | Nucleic acid | HAO1 antagonist |
| dcr-ph1 | Antisense inhibitor | experimental | Nucleic acid | HAO1 antisense inhibitor |
| bbp-711 | Inhibitor | experimental | Small molecule | HAO1 inhibitor |
| bmn 255 | Inhibitor | experimental | Small molecule | HAO1 inhibitor |
| llx-424 | Inhibitor | experimental | Small molecule | HAO1 inhibitor |
| abo-101 | Supplementation | experimental | Gene therapy | HAO1 supplementation |
| glucose oxidase | Supplementation | experimental | Biological | HAO1 supplementation |
| yolt-203 | Supplementation | experimental | Gene therapy | HAO1 supplementation |