← Mechanisms of action
BRAF
SINGLE PROTEINHomo sapiens
Preferred name: Serine/threonine-protein kinase B-raf ChEMBL ↗
Linked proteins
Drugs acting on this target (28)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| cft1946 | Antagonist | experimental | Small molecule | braf |
| xp-102 | Antagonist | experimental | Small molecule | B-Raf |
| arq 736 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| bgb-283 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| cep-32496 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| chir-265 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| dabrafenib (tafinlar) | Inhibitor | approved | Small molecule | BRAF inhibitor |
| dcc-3084 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| encorafenib (braftovi) | Inhibitor | approved | Small molecule | BRAF inhibitor |
| Exarafenib | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| fore8394 | Inhibitor | experimental | Small molecule | Serine/threonine-protein kinase B-raf inhibitor |
| hlx208 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| hsk42360 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| ik-595 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| lut014 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| lut017 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| ly3009120 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| nvp-lgx806 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| pf-07799544 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| plx-3603 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| plx-8394 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| qlh11906 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| regorafenib (stivarga) | Inhibitor | approved | Small molecule | BRAF inhibitor |
| sorafenib (nexavar) | Inhibitor | approved | Small molecule | BRAF inhibitor |
| tak-580 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| tq-b3233 | Inhibitor | experimental | Small molecule | BRAF inhibitor |
| vemurafenib (zelboraf) | Inhibitor | approved | Small molecule | BRAF inhibitor |
| xl281 | Inhibitor | experimental | Small molecule | BRAF inhibitor |