← Mechanisms of action
MC4R
SINGLE PROTEINHomo sapiens
Preferred name: Melanocortin receptor 4 ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| bivamelagon | Agonist | experimental | Small molecule | MC4R agonist |
| bremelanotide (Vyleesi) | Agonist | approved | Peptide | MC4R agonist |
| lb54640 | Agonist | experimental | Small molecule | MC4R agonist |
| mk 0493 | Agonist | experimental | Small molecule | MC4R agonist |
| pf-00446687 | Agonist | experimental | Small molecule | MC4R agonist |
| rm-718 | Agonist | experimental | Small molecule | MC4R agonist |
| setmelanotide (Imcivree) | Agonist | approved | Peptide | MC4R agonist |
| pf-07258669 | Antagonist | experimental | Small molecule | MC4R antagonist |
| tcmcb07 | Antagonist | experimental | Peptide | MC4R antagonist |
| lb64640 | Inhibitor | experimental | Small molecule | MC4R inhibitor |
| azd2820 | Partial agonist | experimental | Small molecule | MC4R partial agonist |