← Mechanisms of action
Plasmodium falciparum
ORGANISMPlasmodium falciparum
Drugs acting on this target (85)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| vrc-malmab0114-00-ab | Adcc | experimental | mAb | Plasmodium falciparum adcc |
| tafenoquine succinate (arakoda) | Antagonist | approved | Small molecule | Plasmodium falciparum antagonist |
| adch63 ama1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| adch63 msp1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| adenovirus-vectored malaria vaccines encoding plasmodium falciparum circumsporozoite protein and apical membrane antigen 1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| ama1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| ama1-c1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| ama1-dico | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| ap10-602 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| bnt165b1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| chad63 rh5 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| chad63/mva me-trap | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| chadox1 ls2 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| d/chad63-cat | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| ep-1300 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp010 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp012 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp013 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp014 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fmp2.1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fp9 cs | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fp9 me-trap | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| fp9-pp | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| gmz2 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| malaria icc-1132 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| malaria transmission-blocking pfs25-pfs25 conjugate vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp 3 long synthetic peptide | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp-1 (fmp-1) with as02a | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp1 42-c1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp1(42)-3d7 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp1(42)-fvo | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp3 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp3 vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp3-crm-vac4all | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| msp3-lsp/aloh | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| mva ama1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| mva cs | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| mva ls2 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| mva rh5 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| mva-msp1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| nmrc-m3v-ad-pfca | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| nmrc-mv-ad-pfa | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| nmrc-mv-ad-pfc | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| p27a vaccine candidate | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| p52-/p36- gap vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pamvac | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pev301 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pev3a | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfama-1-fvo[25-545] | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfcs102 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfcsp dna (vcl-2510) vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfpebs | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs230d1m-epa/alhydrogel | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs230d1m-epa/as01 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs25 vlp- fhcmb | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs25-imx313 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs25m-epa/alhydrogel | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs25m-epa/as01 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfs48/45 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| pfspz | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| placental malaria vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| plasmodium falciparum chimeric prot. 2.9 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| plasmodium falciparum malaria vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| plasmodium falciparum sporozoite | Immunity, active | experimental | Cell therapy | Plasmodium falciparum immunity, active |
| r0.6c transmission blocking vaccine | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| r21 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| r78c | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| rh5.1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| rh5.2 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| SB257049 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| sumayavac-1 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| virosome-formulated synthetic malaria peptides | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| vlpm01 | Immunity, active | experimental | Vaccine | Plasmodium falciparum immunity, active |
| vrc-malmab0100-00-ab | Immunity, passive | experimental | mAb | Plasmodium falciparum immunity, passive |
| act-451840 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| e1018 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| gsk3191607 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| gsk932121 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| mam01 | Inhibitor | experimental | mAb | Plasmodium falciparum inhibitor |
| mmv 533 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| mmv688533 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| sar97276a | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| xc7 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |
| zy19489 | Inhibitor | experimental | Small molecule | Plasmodium falciparum inhibitor |