← Mechanisms of action
MME
SINGLE PROTEINHomo sapiens
Preferred name: Neprilysin ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| J5 | Adcc | experimental | mAb | MME adcc |
| bp102 | Inhibitor | experimental | Small molecule | MME inhibitor |
| daglutril | Inhibitor | experimental | Small molecule | inhibitor - neutral endopeptidase |
| ilepatril | Inhibitor | experimental | Small molecule | Neprilysin inhibitor |
| Racecadotril (redotil) | Inhibitor | experimental | Small molecule | MME inhibitor |
| sacubitril (Entresto) | Inhibitor | approved | Small molecule | MME inhibitor |
| slv-351 | Inhibitor | experimental | Small molecule | MME inhibitor |
| slv334 | Inhibitor | experimental | Small molecule | MME inhibitor |
| slv338 | Inhibitor | experimental | Small molecule | MME inhibitor |
| td-0714 | Inhibitor | experimental | Small molecule | MME inhibitor |
| td-1439 | Inhibitor | experimental | Small molecule | MME inhibitor |