← Mechanisms of action
GRM2
SINGLE PROTEINHomo sapiens
Preferred name: Metabotropic glutamate receptor 2 ChEMBL ↗
Linked proteins
Drugs acting on this target (15)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ly-404039 | Agonist | experimental | Small molecule | GRM2 agonist |
| ly2300559 | Agonist | experimental | Small molecule | GRM2 agonist |
| ly2969822 | Agonist | experimental | Small molecule | GRM2 agonist |
| ly2979165 | Agonist | experimental | Small molecule | GRM2 agonist |
| pomaglumetad | Agonist | experimental | Small molecule | GRM2 agonist |
| bci-1038 | Antagonist | experimental | Small molecule | GRM2 antagonist |
| bci-1283 | Antagonist | experimental | Small molecule | GRM2 antagonist |
| bci-838 | Antagonist | experimental | Small molecule | GRM2 antagonist |
| gate-101 | Antagonist | experimental | Small molecule | GRM2 antagonist |
| ts-161 | Inhibitor | experimental | Small molecule | GRM2 inhibitor |
| decoglurant | Modulator | experimental | Small molecule | GRM2 modulator |
| jnj-40411813 | Modulator | experimental | Small molecule | GRM2 modulator |
| jnj-55375515 | Modulator | experimental | Small molecule | GRM2 modulator |
| azd8529 | Positive allosteric modulator | experimental | Small molecule | GRM2 positive allosteric modulator |
| jnj-40411813 | Positive allosteric modulator | experimental | Small molecule | Metabotropic glutamate receptor 2 positive allosteric modulator |