← Mechanisms of action
SELP
SINGLE PROTEINHomo sapiens
Preferred name: P-selectin ChEMBL ↗
Linked proteins
Drugs acting on this target (8)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| ethamsylate | Activator | experimental | Small molecule | SELP activator |
| inclacumab | Antagonist | experimental | mAb | SELP antagonist |
| rivipansel | Antagonist | experimental | Small molecule | SELP antagonist |
| crizanlizumab (Adakveo) | Blocker | approved | mAb | P-selectin blocker |
| crizanlizumab (Adakveo) | Immunity, passive | approved | mAb | SELP immunity, passive |
| fam-trastuzumab deruxtecan-nxki (Enhertu) | Inhibitor | approved | mAb | SELP inhibitor |
| inclacumab | Inhibitor | experimental | mAb | SELP inhibitor |
| psi-697 | Inhibitor | experimental | Small molecule | SELP inhibitor |