← Mechanisms of action

KLRK1

SINGLE PROTEINHomo sapiens
Preferred name: NKG2-D type II integral membrane protein

Linked proteins

Drugs acting on this target (17)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
allogeneic cart-nkg2d cellsImmunity, passiveexperimentalCell therapyKLRK1 immunity, passive
car-nk cells targeting nkg2d ligandsImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
cccr-nk92 cellsImmunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
cd8+nkg2d+ akt cellImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
cm-cs1 t-cellImmunity, passiveexperimentalCell therapyimmunity, passive - nkg2d
cyad-02Immunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
cyad-101Immunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
kd-025 car-t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
nkg2d car-nkImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
nkg2d car-t cellImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
nkg2d-car-nk92 cellsImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
nkg2dl-targetting chimeric antigen receptor-grafted gamma delta t cellImmunity, passiveexperimentalCell therapyimmunity, passive - KLRK1
nkr-2 car-t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
nkx101Immunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
nnc 0070-0002-0349Immunity, passiveexperimentalCell therapyimmunity, passive - NKG2D
jnj-64304500InhibitorexperimentalmAbKLRK1 inhibitor
nnc0142-0002InhibitorexperimentalmAbKLRK1 inhibitor