← Mechanisms of action
IL2RA
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-2 receptor alpha chain ChEMBL ↗
Linked proteins
Drugs acting on this target (22)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| 8mw2311 | Agonist | experimental | mAb | il2R |
| lyc001 | Agonist | experimental | Recombinant protein | IL2RA agonist |
| mk-6194 | Agonist | experimental | Recombinant protein | IL2RA agonist |
| Nemvaleukin Alfa | Agonist | experimental | Small molecule | IL2RA agonist |
| opl-0301 | Agonist | experimental | Recombinant protein | IL2RA agonist |
| ptx-912 | Agonist | experimental | Recombinant protein | IL2RA agonist |
| transcon il-2 β/γ | Agonist | experimental | Recombinant protein | IL2RA agonist |
| vis171 | Agonist | experimental | Small molecule | IL2RA agonist |
| xtx202 | Agonist | experimental | Recombinant protein | IL2RA agonist |
| anti-Tac | Antagonist | experimental | mAb | IL2RA |
| inolimomab | Antagonist | experimental | mAb | IL2RA antagonist |
| [18f]alf-resca-il2 | Binding agent | experimental | Recombinant protein | IL2R |
| anti-tac(fv)-pe38 | Binding agent | experimental | mAb | IL2RA binding agent |
| camidanlumab tesirine | Binding agent | experimental | mAb | Interleukin-2 receptor alpha chain binding agent |
| y90 humanized anti-tac | Binding agent | experimental | mAb | IL2RA binding agent |
| ba1106 | Inhibitor | experimental | mAb | IL2RA inhibitor |
| inolimomab | Inhibitor | experimental | mAb | IL2RA inhibitor |
| ly3471851 | Inhibitor | experimental | Recombinant protein | IL2RA inhibitor |
| regn10597 | Inhibitor | experimental | mAb | IL2RA inhibitor |
| rm-1995 | Inhibitor | experimental | Small molecule | IL2RA inhibitor |
| xmab27564 | Inhibitor | experimental | mAb | IL2RA inhibitor |
| stk-012 | Partial agonist | experimental | Recombinant protein | IL2RA partial agonist |