← Mechanisms of action

DLL3

SINGLE PROTEINHomo sapiens
Preferred name: Delta-like protein 3 ChEMBL ↗

Linked proteins

Drugs acting on this target (23)

Active Pharmaceutical Ingredient Mechanism Type Approval Status API Type Mechanism of Action
pt217AntagonistexperimentalmAbDLL3
177lu-dtpa-sc16.56Binding agentexperimentalPeptideDLL3 binding agent
qls31904Binding agentexperimentalmAbDLL3
rovalpituzumab tesirineBinding agentexperimentalmAbDelta-like protein 3 binding agent
tarlatamab (IMDELLTRA)Binding agentapprovedmAbDelta-like protein 3 binding agent
amg 119Immunity, passiveexperimentalCell therapyimmunity, passive - DLL3
dll3-car-nk cellsImmunity, passiveexperimentalCell therapyimmunity, passive - DLL3
gc511b car-t cellImmunity, passiveexperimentalCell therapyDLL3 immunity, passive
bi 764532InhibitorexperimentalmAbDLL3 inhibitor
fz-ad005InhibitorexperimentalmAbDLL3 inhibitor
hpn328InhibitorexperimentalmAbDLL3 inhibitor
lb2102InhibitorexperimentalSmall moleculeinhibitor - DLL3
ro7616789InhibitorexperimentalmAbinhibitor - DLL3
rovalpituzumab tesirineInhibitorexperimentalmAbDLL3 inhibitor
sc002InhibitorexperimentalmAbDLL3 inhibitor
sl-172154InhibitorexperimentalmAbDLL3 inhibitor
sys6040InhibitorexperimentalmAbDLL3 inhibitor
tarlatamab (IMDELLTRA)InhibitorapprovedmAbDLL3 inhibitor
225ac-abd147RadiodepletionexperimentalmAbDLL3 radiodepletion
225ac-etn029RadiodepletionexperimentalPeptideDLL3 radiodepletion
111in-abd147RadiopharmaceuticalexperimentalRecombinant proteinDLL3 radiopharmaceutical
111in-etn029RadiopharmaceuticalexperimentalSmall moleculeDLL3 radiopharmaceutical
89zr-dfo-sc16.56RadiopharmaceuticalexperimentalmAbDLL3 radiopharmaceutical