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← Mechanisms of action

GPRC5D

SINGLE PROTEINHomo sapiens
Preferred name: G-protein coupled receptor family C group 5 member D ChEMBL ↗

Linked proteins

Drugs acting on this target (19)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
jnj-79635322Binding agentexperimentalmAbbinding agent - GPRC5D
Talquetamab (Talvey)Binding agentapprovedmAbG-protein coupled receptor family C group 5 member D binding agent
tqb2029Immunity, activeexperimentalmAbGPRC5D immunity, active
act-001 car-nk cellImmunity, passiveexperimentalCell therapyGPRC5D immunity, passive
bcma/gprc5d double car-tImmunity, passiveexperimentalCell therapyimmunity, passive - gprc5d
chimeric antigen receptor t cell o&d-001 injection targeting bcma and gprc5dImmunity, passiveexperimentalCell therapyGPRC5D immunity, passive
ct071Immunity, passiveexperimentalCell therapyGPRC5D immunity, passive
deeptag-gprc5d targeted car t-cellsImmunity, passiveexperimentalCell therapyimmunity, passive - gprc5d
gprc5d-car-tImmunity, passiveexperimentalCell therapyimmunity, passive - gprc5d
mcarh109Immunity, passiveexperimentalCell therapyimmunity, passive - GPRC5D
mcarh109 t cellsImmunity, passiveexperimentalCell therapyimmunity, passive - GPRC5D
ol-101Immunity, passiveexperimentalCell therapyGPRC5D immunity, passive
bms-986453InhibitorexperimentalmAbinhibitor - GPRC5D
gprc5d/cd3 bitesInhibitorexperimentalmAbGPRC5D inhibitor
ibi3003InhibitorexperimentalmAbinhibitor - GPRC5D
lbl-034InhibitorexperimentalmAbinhibitor - GPRC5D
qls32015InhibitorexperimentalmAbinhibitor - GPRC5D
sar446523InhibitorexperimentalSmall moleculeGPRC5D inhibitor
sim0500InhibitorexperimentalmAbGPRC5D inhibitor