← Mechanisms of action
SELE
SINGLE PROTEINHomo sapiens
Preferred name: Selectin E ChEMBL ↗
Linked proteins
Drugs acting on this target (12)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| MDX-11 | Adcc | experimental | mAb | SELE adcc |
| MDX-22 | Adcc | experimental | mAb | SELE adcc |
| PM-81 | Adcc | experimental | mAb | SELE adcc |
| ntx-1088 | Antagonist | experimental | mAb | SELE antagonist |
| pf-07209326 | Antagonist | experimental | Small molecule | SELE antagonist |
| rivipansel | Antagonist | experimental | Small molecule | SELE antagonist |
| uproleselan | Antagonist | experimental | Small molecule | Selectin E antagonist |
| technetium (99m tc) fanolesomab (Neurospec) | Binding agent | withdrawn | mAb | SELE binding agent |
| cdp-850 | Inhibitor | experimental | mAb | SELE inhibitor |
| e-selectin | Inhibitor | experimental | Recombinant protein | SELE inhibitor |
| gi-270384 | Inhibitor | experimental | Small molecule | SELE inhibitor |
| gmi-1359 | Inhibitor | experimental | Small molecule | SELE inhibitor |