CDEK
← Mechanisms of action

CD40-CD40L

PROTEIN-PROTEIN INTERACTIONHomo sapiens

Linked proteins

Drugs acting on this target (18)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
mp0317AgonistexperimentalRecombinant proteinCD40-CD40L agonist
ro7300490AgonistexperimentalRecombinant proteinCD40-CD40L agonist
gm.cd40lImmunity, activeexperimentalVaccineCD40-CD40L immunity, active
gm.cd40l cellsImmunity, activeexperimentalVaccineCD40-CD40L immunity, active
gm.cd40l vaccineImmunity, activeexperimentalVaccineCD40-CD40L immunity, active
gm.cd40l.ccl21Immunity, activeexperimentalVaccineCD40-CD40L immunity, active
il-2 secreting and hcl4ol-expressing autologous b-cll cellsImmunity, passiveexperimentalCell therapyCD40-CD40L immunity, passive
il-2-secreting cd40l-expressing autologous b-cll cellsImmunity, passiveexperimentalVaccineCD40-CD40L immunity, passive
tcrx t cellImmunity, passiveexperimentalCell therapyCD40-CD40L immunity, passive
BNT314InhibitorexperimentalmAbCD40-CD40L inhibitor
frexalimabInhibitorexperimentalmAbCD40-CD40L inhibitor
ibi355InhibitorexperimentalmAbCD40-CD40L inhibitor
ng-350aInhibitorexperimentalGene therapyCD40-CD40L inhibitor
shr-7367InhibitorexperimentalmAbCD40-CD40L inhibitor
tnx-1500InhibitorexperimentalmAbCD40-CD40L inhibitor
adcd40lSupplementationexperimentalGene therapyCD40-CD40L supplementation
adcucd40lSupplementationexperimentalGene therapyCD40-CD40L supplementation
cd40 gene transferSupplementationexperimentalGene therapyCD40-CD40L supplementation