← Mechanisms of action
leuS
SINGLE PROTEINMycobacterium tuberculosis H37Rv
Preferred name: Leucine--tRNA ligase ChEMBL ↗
Linked proteins
Drugs acting on this target (4)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| Fluciclovine (Axumin) | Antagonist | approved | Small molecule | leuS antagonist |
| an2718 | Inhibitor | experimental | Small molecule | leuS inhibitor |
| epetraborole | Inhibitor | experimental | Small molecule | leuS inhibitor |
| gsk2251052 | Inhibitor | experimental | Small molecule | leuS inhibitor |