CDEK by Data4ThePeople
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← Mechanisms of action

PMEL

SINGLE PROTEINHomo sapiens
Preferred name: Melanocyte protein PMEL ChEMBL ↗

Linked proteins

Drugs acting on this target (15)

Active Pharmaceutical Ingredient Mechanism Type ▲ Approval Status API Type Mechanism of Action
afamelanotide (Scenesse)AgonistapprovedPeptidePMEL agonist
tebentafusp (Kimmtrak)Binding agentapprovedRecombinant proteinPMEL binding agent
dendritic cell-gp100-mart-1 antigen vaccineImmunity, activeexperimentalVaccinePMEL immunity, active
gp-100 peptide vaccineImmunity, activeexperimentalVaccinePMEL immunity, active
gp100-fowlpox vaccineImmunity, activeexperimentalVaccinePMEL immunity, active
gp209-2m antigenImmunity, activeexperimentalBiologicalPMEL immunity, active
mart-1, gp100, tyrosinase peptidesImmunity, activeexperimentalVaccinePMEL immunity, active
mdx-1379Immunity, activeexperimentalVaccinePMEL immunity, active
anti-gp 100:154 tcell receptor peripheral blood lymphocyteImmunity, passiveexperimentalCell therapyPMEL immunity, passive
autologous anti-gp 100:154-162 t-cell receptor gene-engineered peripheral blood lymphocytesImmunity, passiveexperimentalCell therapyPMEL immunity, passive
autologous anti-gp 100:154-162 t-cell receptor gene-engineered tumor infiltrating lymphocytesImmunity, passiveexperimentalCell therapyPMEL immunity, passive
gpa-trimar-tImmunity, passiveexperimentalCell therapyPMEL immunity, passive
lvgp120duocar-t cellsImmunity, passiveexperimentalCell therapyPMEL immunity, passive
dyp688InhibitorexperimentalmAbPMEL inhibitor
bmx-001OtherexperimentalSmall moleculePMEL other