← Mechanisms of action
ICOS
SINGLE PROTEINHomo sapiens
Preferred name: Inducible T-cell costimulator ChEMBL ↗
Linked proteins
Drugs acting on this target (11)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| gsk3359609 | Agonist | experimental | mAb | Inducible T-cell costimulator agonist |
| jtx-2011 | Agonist | experimental | mAb | Inducible T-cell costimulator agonist |
| alpn-101 | Inhibitor | experimental | mAb | ICOS inhibitor |
| bms-986226 | Inhibitor | experimental | mAb | ICOS inhibitor |
| gsk3359609 | Inhibitor | experimental | mAb | ICOS inhibitor |
| jtx-2011 | Inhibitor | experimental | mAb | ICOS inhibitor |
| ky1044 | Inhibitor | experimental | mAb | ICOS inhibitor |
| medi-570 | Inhibitor | experimental | mAb | ICOS inhibitor |
| Prezalumab | Inhibitor | experimental | mAb | ICOS inhibitor |
| Rozibafusp alfa | Inhibitor | experimental | Small molecule | Inducible T-cell costimulator inhibitor |
| xmab23104 | Inhibitor | experimental | mAb | ICOS inhibitor |