← Mechanisms of action
IL4R
SINGLE PROTEINHomo sapiens
Preferred name: Interleukin-4 receptor subunit alpha ChEMBL ↗
Linked proteins
Drugs acting on this target (17)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| dupilumab (dupixent) | Antagonist | approved | mAb | IL4R antagonist |
| sim0718 | Antagonist | experimental | Small molecule | IL4R antagonist |
| tqh2722 | Antagonist | experimental | mAb | IL4RA |
| il-4(38-37)-pe38kdel | Binding agent | experimental | Recombinant protein | IL4R binding agent |
| amg 317 | Inhibitor | experimental | mAb | IL4R inhibitor |
| cbp-201 | Inhibitor | experimental | mAb | IL4R inhibitor |
| cm310 | Inhibitor | experimental | mAb | IL4R inhibitor |
| dupilumab (dupixent) | Inhibitor | approved | mAb | IL4R inhibitor |
| gr1802 | Inhibitor | experimental | Small molecule | IL4R inhibitor |
| ibi3002 | Inhibitor | experimental | mAb | IL4R inhibitor |
| medi9314 | Inhibitor | experimental | mAb | IL4R inhibitor |
| nm26-2198 | Inhibitor | experimental | mAb | IL4R inhibitor |
| rc1416 | Inhibitor | experimental | mAb | IL4R inhibitor |
| shr-1819 | Inhibitor | experimental | Small molecule | IL4R inhibitor |
| stapokibatrt | Inhibitor | experimental | mAb | IL4R inhibitor |
| elarekibep | Supplementation | experimental | Recombinant protein | IL4R supplementation |
| interleukin-4 | Supplementation | experimental | Recombinant protein | IL4R supplementation |