← Mechanisms of action
ANGPT2
SINGLE PROTEINHomo sapiens
Preferred name: Angiopoietin-2 ChEMBL ↗
Linked proteins
Drugs acting on this target (13)
| Active Pharmaceutical Ingredient | Mechanism Type ▲ | Approval Status | API Type | Mechanism of Action |
|---|---|---|---|---|
| askg712 | Antagonist | experimental | Recombinant protein | ANGPT2 antagonist |
| faricimab (Vabysmo) | Antagonist | approved | mAb | ANGPT2 antagonist |
| ibi324 | Antagonist | experimental | mAb | ANGPT2 antagonist |
| amg-780 | Inhibitor | experimental | mAb | ANGPT2 inhibitor |
| cvx-060 | Inhibitor | experimental | mAb | ANGPT2 inhibitor |
| ema401 | Inhibitor | experimental | Small molecule | ANGPT2 inhibitor |
| exg102 | Inhibitor | experimental | Gene therapy | ANGPT2 inhibitor |
| faricimab (Vabysmo) | Inhibitor | approved | mAb | Angiopoietin-2 inhibitor |
| medi-3617 | Inhibitor | experimental | mAb | ANGPT2 inhibitor |
| nesvacumab | Inhibitor | experimental | mAb | ANGPT2 inhibitor |
| pf-04856884 | Inhibitor | experimental | Recombinant protein | ANGPT2 inhibitor |
| trebananib | Inhibitor | experimental | Small molecule | ANGPT2 inhibitor |
| vanucizumab | Inhibitor | experimental | mAb | ANGPT2 inhibitor |