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Highest phase reached
Phase 3
First clinical trial
Sep 1, 2003Last known activity
Nov 10, 2017
Acquired by Merck on Dec 9, 2019
Timeline
1990s
- Jun 1, 1993
ArQule— Founded
2000s
- Jan 22, 2001
Camitro— Acquired
2010s
- Jul 18, 2013
Cyclis Pharmaceuticals— Acquired
- Dec 9, 2019
Merck— Acquired By
Drugs by trial phase (22 distinct, 37 trials)
Phase 3 (2 own, 0 via acquisition)
Phase 2 (10 own, 0 via acquisition)
Phase 1 (10 own, 0 via acquisition)
Indications
Studied for
- Adenocarcinoma
- Carcinoma
- Carcinoma, Hepatocellular
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Cholangiocarcinoma
- Endometrial Neoplasms
- Head and Neck Neoplasms
- Leiomyosarcoma
- Leukemia
- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukemia, Lymphoid
- Lung Neoplasms
- Lymphoma
- Lymphoma, B-Cell
- Lymphoma, B-Cell, Marginal Zone
- Lymphoma, Follicular
- Lymphoma, Large B-Cell, Diffuse
- Lymphoma, Mantle-Cell
- Neoplasms
- Ovarian Neoplasms
- Pancreatic Neoplasms
- Proteus Infections
- Proteus Syndrome
- Sarcoma
- Sarcoma, Alveolar Soft Part
- Sarcoma, Clear Cell
- Squamous Cell Carcinoma of Head and Neck
- Stomach Neoplasms
- Syndrome
- Waldenstrom Macroglobulinemia
Subsidiaries (2 direct, 2 total across the full acquisition tree)
Recent trials (37)
- NCT03317366Lead sponsorN/A—
- NCT03230318Lead sponsorPhase 2Nov 10, 2017
- NCT03162536Lead sponsorPhase 1Jul 1, 2017
- NCT03094832Lead sponsorPhase 1/Phase 2May 30, 2017
- NCT02761694Lead sponsorPhase 1Jun 1, 2016
- NCT02476955Lead sponsorPhase 1Jun 1, 2015
- NCT01755767CollaboratorPhase 3Dec 1, 2012
- NCT01752920Lead sponsorPhase 1/Phase 2Dec 1, 2012
- NCT01502800CollaboratorPhase 1Dec 1, 2011
- NCT01473095Lead sponsorPhase 1Nov 1, 2011
- NCT01395758Lead sponsorPhase 2Jul 1, 2011
- NCT01244191CollaboratorPhase 3Nov 1, 2010
- NCT01225536Lead sponsorPhase 1Oct 1, 2010
- NCT01178411Lead sponsorPhase 1/Phase 2Aug 1, 2010
- NCT01149720CollaboratorPhase 1Jul 1, 2010
Details
- Founded
- Woburn, MA, US Jun 1, 1993
- Last known activity
- Nov 10, 2017