Thrombotic Microangiopathies
Diseases that result in THROMBOSIS in MICROVASCULATURE. The two most prominent diseases are PURPURA, THROMBOTIC THROMBOCYTOPENIC; and HEMOLYTIC-UREMIC SYNDROME. Multiple etiological factors include VASCULAR ENDOTHELIAL CELL damage due to SHIGA TOXIN; FACTOR H deficiency; and aberrant VON WILLEBRAND FACTOR formation.
Subtype terms (2)
More specific conditions that are subtypes of Thrombotic Microangiopathies in the MeSH hierarchy.
- Hemolytic-Uremic Syndrome
7 drugs (6 approved, 1 experimental)
- Purpura, Thrombocytopenic
10 drugs (9 approved, 1 experimental)
Drugs by status
Approved for this indication (1)
Phase 3 trials (4)
Phase 2 trials (2)
Phase 1 trials (1)
Other trials (1)
Organizations
Organization Involved with Phase 3 Indications (4)
Organization Involved with Phase 2 Indications (3)
Organization Involved with Other Experimental Indications (1)