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Jumonji Domain-Containing Histone Demethylases

A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.

Subtype terms (1)

More specific conditions that are subtypes of Jumonji Domain-Containing Histone Demethylases in the MeSH hierarchy.