A family of structurally related proteins that are induced by CYTOKINES and negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. SOCS proteins contain a central SH2 DOMAIN and a C-terminal region of homology known as the SOCS box.
Subtype terms (2)
More specific conditions that are subtypes of Suppressor of Cytokine Signaling Proteins in the MeSH hierarchy.