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Tumor Necrosis Factors

A family of proteins that were originally identified by their ability to cause NECROSIS of NEOPLASMS. Their necrotic effect on cells is mediated through TUMOR NECROSIS FACTOR RECEPTORS which induce APOPTOSIS.

Subtype terms (18)

More specific conditions that are subtypes of Tumor Necrosis Factors in the MeSH hierarchy.

  • 4-1BB Ligand
  • B-Cell Activating Factor
  • CD27 Ligand
  • CD30 Ligand
  • CD40 Ligand
  • Cytokine TWEAK
  • Ectodysplasins
  • Fas Ligand Protein
  • Lymphotoxin-alpha
  • Lymphotoxin alpha1, beta2 Heterotrimer
  • Lymphotoxin-beta
  • OX40 Ligand
  • RANK Ligand

    1 drug approved

  • TNF-Related Apoptosis-Inducing Ligand
  • Tumor Necrosis Factor-alpha

    1 drug approved

  • Tumor Necrosis Factor Ligand Superfamily Member 13
  • Tumor Necrosis Factor Ligand Superfamily Member 14
  • Tumor Necrosis Factor Ligand Superfamily Member 15

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