Chromosome Disorders
Clinical conditions caused by an abnormal chromosome constitution in which there is extra or missing chromosome material (either a whole chromosome or a chromosome segment). (from Thompson et al., Genetics in Medicine, 5th ed, p429)
Subtype terms (20)
More specific conditions that are subtypes of Chromosome Disorders in the MeSH hierarchy.
- 22q11 Deletion Syndrome
7 drugs (6 approved, 1 experimental)
- Angelman Syndrome
15 drugs (5 approved, 10 experimental)
- Beckwith-Wiedemann Syndrome
8 drugs approved
- Branchio-Oto-Renal Syndrome
- Cri-du-Chat Syndrome
- De Lange Syndrome
2 drugs approved
- Down Syndrome
77 drugs (60 approved, 17 experimental)
- Holoprosencephaly
- Jacobsen Distal 11q Deletion Syndrome
- Prader-Willi Syndrome
33 drugs (17 approved, 16 experimental)
- Rubinstein-Taybi Syndrome
1 drug approved
- Sex Chromosome Disorders
1 drug approved
- Silver-Russell Syndrome
1 drug approved
- Smith-Magenis Syndrome
3 drugs (2 approved, 1 experimental)
- Sotos Syndrome
- Trisomy 13 Syndrome
- Trisomy 18 Syndrome
- WAGR Syndrome
- Williams Syndrome
8 drugs (7 approved, 1 experimental)
- Wolf-Hirschhorn Syndrome
Drugs by status
Phase 4 trials (1)
Phase 2 trials (3)
Other trials (1)
Organizations
Organization Involved with Phase 3 Indications (1)
Organization Involved with Phase 2 Indications (7)
Organization Involved with Other Experimental Indications (5)