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IndicationsMechanismsTrialsFDA ApprovalsAbout
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Hyperammonemia

Elevated level of AMMONIA in the blood. It is a sign of defective CATABOLISM of AMINO ACIDS or ammonia to UREA.

Drugs by status

Approved for this indication (5)

  • carglumic acid
  • phenylacetic acid
  • sodium phenylbutyrate
  • sodium benzoate
  • benzyl benzoate

Phase 2 trials (1)

  • tnp-2092

Phase 1 trials (1)

  • pbi-4050

Organizations

Organization Involved with Phase 3 Indications (3)

  • National Institutes of Health (NIH)
  • Children's National Research Institute
  • Children's National Medical Center

Organization Involved with Phase 2 Indications (9)

  • Ocera Therapeutics
  • University of Pennsylvania
  • University of Pittsburgh
  • Case Western Reserve University
  • Harvard University
  • Stanford University
  • University of California, Los Angeles
  • Icahn School of Medicine at Mount Sinai
  • University of Colorado

Organization Involved with Phase 1 Indications (2)

  • National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  • University of Utah

Organization Involved with Other Experimental Indications (1)

  • Institute of Liver and Biliary Sciences, India

ICD-10 crosswalk

  • E72.20 — Disorder of urea cycle metabolism, unspecified

CDEK

The Clinical Drug Experience Knowledgebase — tracking drugs, sponsoring organizations, and clinical trials from first-in-human testing through approval.

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