Transposition of Great Vessels
A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.
Subtype terms (2)
More specific conditions that are subtypes of Transposition of Great Vessels in the MeSH hierarchy.
- Congenitally Corrected Transposition of the Great Arteries
- Double Outlet Right Ventricle
2 drugs (1 approved, 1 experimental)
Drugs by status
Phase 4 trials (1)
Phase 3 trials (1)
Phase 2 trials (3)
Organizations
Organization Involved with Phase 4 Indications (3)
Organization Involved with Phase 3 Indications (3)
Organization Involved with Phase 2 Indications (7)
Organization Involved with Phase 1 Indications (2)
Organization Involved with Other Experimental Indications (1)