Klippel-Trenaunay-Weber Syndrome

A congenital disorder that is characterized by a triad of capillary malformations (HEMANGIOMA), venous malformations (ARTERIOVENOUS FISTULA), and soft tissue or bony hypertrophy of the limb. This syndrome is caused by mutations in the VG5Q gene which encodes a strong angiogenesis stimulator.

Drugs by status

Phase 2 trials (1)

rly-2608

Organizations

Organization Involved with Phase 3 Indications (5)

Pfizer
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
University of Cincinnati

Organization Involved with Phase 2 Indications (5)

Novartis
GW Pharmaceuticals Ltd.
Baylor University
Clinica Universidad de Navarra
Faneca 66 Foundation

Organization Involved with Phase 1 Indications (2)

Thomas Jefferson University
University of Medicine and Dentistry of New Jersey

ICD-10 crosswalk

Q87.2 — Congenital malformation syndromes predominantly involving limbs