Calcinosis Cutis

Pathological deposition of calcium in the skin and subcutaneous tissue. Excessive calcification of the skin may be associated with underlying diseases that cause tissue damage (e.g. EHLERS-DANLOS SYNDROME; PSEUDOXANTHOMA ELASTICUM; ROTHMUND-THOMSON SYNDROME; and WERNER SYNDROME) or that cause abnormal calcium and phosphate metabolism (e.g., CALCIPHYLAXIS; CHRONIC KIDNEY FAILURE; HYPERPARATHYROIDISM; and SARCOIDOSIS).