Chapter 14 - Diseases of the genitourinary system (N00-N99)»Glomerular diseases (N00-N08)»Nephrotic syndrome (N04)

N04

Nephrotic syndrome

Sub-codes (10)

Related indications (MeSH) (2)

Nephrosis, Lipoid15 drugs (10 approved, 5 experimental)

A kidney disease with no or minimal histological glomerular changes on light microscopy and with no immune deposits. It is characterized by lipid accumulation in the epithelial cells of KIDNEY TUBULES and in the URINE. Patients usually show NEPHROTIC SYNDROME indicating the presence of PROTEINURIA with accompanying EDEMA.

Nephrotic Syndrome55 drugs (46 approved, 9 experimental)

A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.