Chapter 13 - Diseases of the musculoskeletal system and connective tissue (M00-M99)»Systemic connective tissue disorders (M30-M36)»Other overlap syndromes (M35.1)
M35.1
Other overlap syndromes
Related indications (MeSH) (1)
Mixed Connective Tissue Disease5 drugs (3 approved, 2 experimental)
A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a speckled epidermal nuclear staining pattern on direct immunofluorescence.