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Chapter 6 - Diseases of the nervous system (G00-G99)»Extrapyramidal and movement disorders (G20-G26)»Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski] (G23.1)

G23.1

Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]

Related indications (MeSH) (1)

Supranuclear Palsy, Progressive51 drugs (24 approved, 27 experimental)

A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)