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Chapter 6 - Diseases of the nervous system (G00-G99)»Extrapyramidal and movement disorders (G20-G26)»Hallervorden-Spatz disease (G23.0)

G23.0

Hallervorden-Spatz disease

Related indications (MeSH) (1)

Pantothenate Kinase-Associated Neurodegeneration2 drugs (1 approved, 1 experimental)

A rare autosomal recessive degenerative disorder which usually presents in late childhood or adolescence. Clinical manifestations include progressive MUSCLE SPASTICITY; hyperreflexia; MUSCLE RIGIDITY; DYSTONIA; DYSARTHRIA; and intellectual deterioration which progresses to severe dementia over several years. (From Adams et al., Principles of Neurology, 6th ed, p972; Davis & Robertson, Textbook of Neuropathology, 2nd ed, pp972-929)