Chapter 4 - Endocrine, nutritional and metabolic diseases (E00-E89)»Disorders of other endocrine glands (E20-E35)»Primary adrenocortical insufficiency (E27.1)
E27.1
Primary adrenocortical insufficiency
Related indications (MeSH) (1)
Addison Disease10 drugs (8 approved, 2 experimental)
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.