Chapter 3 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)»Certain disorders involving the immune mechanism (D80-D89)»Autoimmune lymphoproliferative syndrome [ALPS] (D89.82)
D89.82
Autoimmune lymphoproliferative syndrome [ALPS]
Related indications (MeSH) (1)
Autoimmune Lymphoproliferative Syndrome7 drugs (5 approved, 2 experimental)
Rare congenital lymphoid disorder due to mutations in certain Fas-Fas ligand pathway genes. Known causes include mutations in FAS, TNFSF6, NRAS, CASP8, and CASP10 proteins. Clinical features include LYMPHADENOPATHY; SPLENOMEGALY; and AUTOIMMUNITY.