Chapter 3 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)»Certain disorders involving the immune mechanism (D80-D89)»Major histocompatibility complex class I deficiency (D81.6)
D81.6
Major histocompatibility complex class I deficiency
Related indications (MeSH) (1)
Severe Combined Immunodeficiency42 drugs (27 approved, 15 experimental)
Group of rare congenital disorders characterized by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an X-linked or autosomal recessive defect. Mutations occurring in many different genes cause human Severe Combined Immunodeficiency (SCID).