Chapter 3 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)»Other disorders of blood and blood-forming organs (D70-D77)»Functional disorders of polymorphonuclear neutrophils (D71)
D71
Functional disorders of polymorphonuclear neutrophils
Related indications (MeSH) (1)
Granulomatous Disease, Chronic52 drugs (30 approved, 22 experimental)
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.