Chapter 3 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)»Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)»Other primary thrombophilia (D68.59)
D68.59
Other primary thrombophilia
Related indications (MeSH) (4)
An absence or reduced level of Antithrombin III leading to an increased risk for thrombosis.
An absence or deficiency in PROTEIN C which leads to impaired regulation of blood coagulation. It is associated with an increased risk of severe or premature thrombosis. (Stedman's Med. Dict., 26th ed.)
An autosomal dominant disorder showing decreased levels of plasma protein S antigen or activity, associated with venous thrombosis and pulmonary embolism. PROTEIN S is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated PROTEIN C (also a vitamin K-dependent protein), and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. Treatment with heparin for acute thrombotic processes is usually followed by maintenance administration of coumarin drugs for the prevention of recurrent thrombosis. (From Harrison's Principles of Internal Medicine, 12th ed, p1511; Wintrobe's Clinical Hematology, 9th ed, p1523)
A disorder of HEMOSTASIS in which there is a tendency for the occurrence of THROMBOSIS.