Chapter 3 - Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)»Coagulation defects, purpura and other hemorrhagic conditions (D65-D69)»Activated protein C resistance (D68.51)
D68.51
Activated protein C resistance
Related indications (MeSH) (1)
Activated Protein C Resistance2 drugs (2 approved)
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.