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xanthophyll

Small moleculeexperimental

Xanthophylls are yellow pigments that occur widely in nature and form one of two major divisions of the carotenoid group; the other division is formed by the carotenes. The name is from Greek: xanthos (ξανθός), meaning "yellow", and phyllon (φύλλον), meaning "leaf"), due to their formation of the yellow band seen in early chromatography of leaf pigments. — Wikipedia

Clinical trial activity

32 trials · 44 clinical orgs · 0 marketing orgs

Phase 1
5
Phase 2
10
Phase 3
5
Phase 4
1

Earliest trial started Sep 1, 2000 (NCT00006202)

Timeline

2000s

  1. Jan 1, 2000

    Earliest Phase 2 Sponsor(trial)

  2. Jan 1, 2001

    Earliest Phase 1 Sponsor(trial)

  3. Jan 1, 2003

    Earliest Phase 3 Sponsor(trial)

Indications

Approved for

Studied for

Mechanism of action

  • Unspecified targetUnclear

    Unclear

Chemistry & pharmacology

Loading structure…

SMILES

CC1=C[C@H](O)CC(C)(C)[C@H]1/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C
Mol. weight
568.89 g/mol
Lipinski Ro5
2 violation(s)
Rule of 3
No
Chirality
Single Stereoisomer
Inorganic
No
Polymer
No

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • leutein
  • lutein
  • lutein
  • lutein
  • lutein
  • lutein
  • lutein
  • lutein
  • utein
  • xanthophyll
  • xanthophyll
  • xanthophyll
  • xanthophyll
  • xantofyl
  • xantofyl

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT03113864N/AApr 15, 2017DSM, Kemin Foods LC
NCT02136303N/AFeb 1, 2015Friedrich Schiller University
NCT02379169N/AFeb 1, 2015Aromtech Ltd., University of Turku
NCT02200263N/ANov 1, 2014Clark Charitable Foundation Inc., Johns Hopkins University
NCT01694680N/AOct 1, 2012Newtricious R&D BV, Sprim Consulting, United States Department of Agriculture
NCT02017418N/AFeb 1, 2012University of Georgia, ZeaVision, Inc.
NCT01404845N/ASep 1, 2011Affordance
NCT01321268N/AMay 1, 2011DSM, Pontifical Catholic University of Rio Grande do Sul
NCT01400763N/AMay 1, 2011Wageningen University
NCT01778231N/AMar 1, 2011Queen's University, Belfast
NCT02062034Phase 2Feb 1, 2011Instituto Mexicano del Seguro Social, University of Guadalajara
NCT01269697Phase 3Jan 1, 2011Laboratoires Thea, University of Bordeaux
NCT02068807Phase 1/Phase 2 (Phase 2)Jan 1, 2011University of Florence, University of Siena
NCT01534533Phase 2/Phase 3 (Phase 3)Jun 1, 2010Peking University
NCT01528605N/AJun 1, 2010Peking University
NCT01056094Phase 1/Phase 2 (Phase 2)Apr 1, 2010Jiao Tong University, Peking University
NCT01048476Phase 1/Phase 2 (Phase 2)Sep 1, 2009Peking University
NCT00909090Phase 2/Phase 3 (Phase 3)May 1, 2009University of Georgia
NCT01648660N/AMay 1, 2009Friedrich Schiller University, University of Leipzig
NCT00763659N/AMay 1, 2008Friedrich Schiller University, University of Leipzig
Showing 20 of 32 trials
Page 1 / 2

Organizations

Research & Development (44)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
National Eye Institute (NEI)Government5542000
Peking UniversityAcademic/Hospital4432009
Friedrich Schiller UniversityAcademic/Hospital3312008
DSMFor profit2112011
National Center for Complementary and Integrative Health (NCCIH)Government2122001
University of GeorgiaAcademic/Hospital2222009
University of LeipzigAcademic/Hospital2012008
AffordanceAcademic/Hospital1112011
AlconFor profit1012004
Aromtech Ltd.For profit1012015
Chrysantis, Inc.For profit1112007
Clark Charitable Foundation Inc.Academic/Hospital1012014
CognisFor profit1012007
Department of Veteran AffairsGovernment1012007
Harvard UniversityAcademic/Hospital1012003
Instituto Mexicano del Seguro SocialGovernment1012011
Jiao Tong UniversityAcademic/Hospital1012010
Johns Hopkins UniversityAcademic/Hospital1112014
Kemin Foods LCFor profit1112017
KowaFor profit1012007
44 organizations
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