Ganfeborole
Small moleculeexperimental
Clinical trial activity
5 trials · 23 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Apr 2, 2017 (NCT03075410)
Timeline
Indications
Mechanism of action
- Mycobacterium tuberculosisINHIBITOR
Mycobacterium tuberculosis inhibitor
Chemistry & pharmacology
Loading structure…
SMILES
NC[C@H]1OB(O)c2c(OCCO)ccc(Cl)c21- Mol. weight
- 257.48 g/mol
- Chirality
- Single Stereoisomer
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- ChEMBLCHEMBL4116378 ↗
Also known as
- gsk3036656
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06354257 | Phase 1 | Apr 5, 2024 | GlaxoSmithKline |
| NCT06114628 | Phase 2 | Dec 8, 2023 | German Center for Infection Research, GlaxoSmithKline, Government of France, Janssen Pharmaceutica NV, KNCV Tuberculosis Foundation, Otsuka, Radboud University, Research Center Borstel, TASK Applied Science, TB Alliance, Tuberculosis Network European Trialsgroup, University of California, San Francisco, University of Cambridge, University of Hamburg, University of Liverpool, University of London, University of Milan, University of Oxford, University of Porto, University of St Andrews, Uppsala University, Vita-Salute University of Milano. Italy |
| NCT05382312 | Phase 2 | Jul 26, 2022 | Click-TB Consortium, GlaxoSmithKline |
| NCT03557281 | Phase 2 | Dec 12, 2018 | GlaxoSmithKline |
| NCT03075410 | Phase 1 | Apr 2, 2017 | GlaxoSmithKline |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (23)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| GlaxoSmithKline | For profit | 5 | 4 | 2 | 2017 |
| Click-TB Consortium | Academic/Hospital | 1 | 0 | 1 | 2022 |
| German Center for Infection Research | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Government of France | Government | 1 | 0 | 1 | 2023 |
| Janssen Pharmaceutica NV | For profit | 1 | 0 | 1 | 2023 |
| KNCV Tuberculosis Foundation | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Otsuka | For profit | 1 | 0 | 1 | 2023 |
| Radboud University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Research Center Borstel | Academic/Hospital | 1 | 0 | 1 | 2023 |
| TASK Applied Science | For profit | 1 | 0 | 1 | 2023 |
| TB Alliance | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Tuberculosis Network European Trialsgroup | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of California, San Francisco | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of Cambridge | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of Hamburg | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of Liverpool | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of London | Academic/Hospital | 1 | 1 | 1 | 2023 |
| University of Milan | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of Oxford | Academic/Hospital | 1 | 0 | 1 | 2023 |
| University of Porto | Academic/Hospital | 1 | 0 | 1 | 2023 |
23 organizations
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