gluten
Allergenexperimental
Gluten is a structural protein complex naturally found in certain cereal grains. The term gluten usually refers to the elastic network of a wheat grain's proteins, gliadin and glutenin primarily, which forms readily with the addition of water and often kneading in the case of bread dough. The types of grains that contain gluten include all species of wheat, and barley, rye, and some cultivars of oat; moreover, cross hybrids of any of these cereal grains also contain gluten, e.g. triticale. Gluten makes up 75–85% of the total protein in bread wheat. — Wikipedia
Clinical trial activity
35 trials · 39 clinical orgs · 0 marketing orgs
Phase 1
3
Phase 2
3
Phase 3
2
Phase 4
0
Earliest trial started Sep 1, 2006 (NCT01100099)
Timeline
Indications
Mechanism of action
- GlutenImmunity, desensitized
Gluten immunity, desensitized
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaGluten ↗
Also known as
- gluten
- gluten
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06900946 | N/A | Apr 1, 2025 | National Nutrition and Food Technology Institute |
| NCT05894746 | N/A | May 4, 2023 | The Ekhaga Foundation, Stockholm, Sweden, University of Gothenburg, University of Skövde |
| NCT05636293 | Phase 2 | Jan 1, 2023 | Harvard University, Pfizer |
| NCT05209568 | N/A | Oct 1, 2022 | Celiac Disease Foundation, Harvard University, University of Colorado |
| NCT04530123 | Phase 2 | Apr 29, 2021 | Takeda |
| NCT04604795 | Phase 1 | Nov 6, 2020 | GlaxoSmithKline |
| NCT04614571 | N/A | Nov 2, 2020 | Regeneron |
| NCT04054544 | Early Phase 1 (Phase 1) | Oct 7, 2019 | Merck |
| NCT03664531 | N/A | Sep 30, 2018 | McMaster University |
| NCT03653689 | N/A | Sep 10, 2018 | Chalmers University of Technology, Uppsala University |
| NCT03714646 | N/A | Sep 5, 2018 | Maastricht University |
| NCT03409796 | Early Phase 1 (Phase 1) | Apr 24, 2018 | Takeda |
| NCT03288831 | N/A | Oct 10, 2017 | Mayo Clinic |
| NCT03183609 | N/A | Jul 10, 2017 | University of Maryland |
| NCT03798249 | N/A | May 11, 2017 | Katholieke Universiteit Leuven |
| NCT02464150 | N/A | Apr 1, 2017 | Osaka University, South-Eastern Norway Regional Health Authority, Stiftelsen Helse og Rehabilitering, University of Oslo |
| NCT03798262 | N/A | Feb 16, 2017 | Katholieke Universiteit Leuven |
| NCT02936297 | N/A | Jun 1, 2016 | Thomas Jefferson University |
| NCT03129906 | N/A | Sep 25, 2015 | Federal University of Minas Gerais |
| NCT01506349 | N/A | Jun 1, 2015 | Harvard University |
Showing 20 of 35 trials
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Organizations
Research & Development (39)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Harvard University | Academic/Hospital | 5 | 5 | 2 | 2008 |
| Aarhus University | Academic/Hospital | 3 | 3 | 1 | 2009 |
| Katholieke Universiteit Leuven | Academic/Hospital | 2 | 2 | 1 | 2017 |
| Nordic Centre of Excellence | Academic/Hospital | 2 | 0 | 1 | 2009 |
| Osaka University | Academic/Hospital | 2 | 2 | 2 | 2006 |
| South-Eastern Norway Regional Health Authority | Government | 2 | 0 | 2 | 2006 |
| Takeda | For profit | 2 | 2 | 2 | 2018 |
| The Danish Obesity Research Centre | Academic/Hospital | 2 | 0 | 1 | 2009 |
| University of Copenhagen | Academic/Hospital | 2 | 1 | 1 | 2012 |
| University of Oslo | Academic/Hospital | 2 | 0 | 2 | 2006 |
| Celiac Disease Foundation | Academic/Hospital | 1 | 0 | 1 | 2022 |
| Chalmers University of Technology | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Federal University of Minas Gerais | Academic/Hospital | 1 | 1 | 1 | 2015 |
| GlaxoSmithKline | For profit | 1 | 1 | 1 | 2020 |
| Hospital Mutua de Terrassa | Academic/Hospital | 1 | 1 | 1 | 2011 |
| ImmusanT, Inc. | For profit | 1 | 0 | 1 | 2013 |
| Joslin Diabetes Center | Academic/Hospital | 1 | 1 | 1 | 2013 |
| Maastricht University | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Mayo Clinic | Academic/Hospital | 1 | 1 | 1 | 2017 |
| McMaster University | Academic/Hospital | 1 | 1 | 1 | 2018 |
39 organizations
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