ebola vaccine
Trade name: Ervebo
VaccineapprovedBreakthrough Therapy FDA
Approved
Dec 19, 2019
Ebola vaccines are vaccines either approved or in development to prevent Ebola. As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. During the early 21st century, several vaccine candidates displayed efficacy to protect nonhuman primates against lethal infection. — Wikipedia
Clinical trial activity
4 trials · 11 clinical orgs · 1 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
1
Phase 4
0
Earliest trial started Feb 1, 2010 (NCT00997607)
Timeline
Indications
Approved for
Mechanism of action
- EbolavirusImmunity, active
Ebolavirus immunity, active
Approval history
- approvedPriority reviewBreakthroughDec 19, 2019
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaEbola vaccine ↗
Also known as
- ebola vaccine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT06126822 | Phase 3 | Mar 31, 2024 | Institute of Tropical Medicine, Belgium |
| NCT02718469 | Phase 1 | Dec 22, 2015 | Accelovance, Department of Defense, Optimal Research, Profectus BioSciences, Inc. |
| NCT02575456 | Phase 2 | Oct 1, 2015 | Beijing Institute of Biotechnology, Government of China, Ministry of Health & Sanitation, Tianjin Cansino Biotechnology Inc |
| NCT00997607 | Phase 1 | Feb 1, 2010 | Makerere University, National Institute of Allergy and Infectious Diseases (NIAID) |
Showing 4 of 4 trials
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Organizations
Research & Development (11)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Accelovance | For profit | 1 | 0 | 1 | 2015 |
| Beijing Institute of Biotechnology | Academic/Hospital | 1 | 0 | 1 | 2015 |
| Department of Defense | Government | 1 | 0 | 1 | 2015 |
| Government of China | Government | 1 | 1 | 1 | 2015 |
| Institute of Tropical Medicine, Belgium | Academic/Hospital | 1 | 1 | 1 | 2024 |
| Makerere University | Academic/Hospital | 1 | 0 | 1 | 2010 |
| Ministry of Health & Sanitation | Government | 1 | 0 | 1 | 2015 |
| National Institute of Allergy and Infectious Diseases (NIAID) | Government | 1 | 1 | 1 | 2010 |
| Optimal Research | For profit | 1 | 0 | 1 | 2015 |
| Profectus BioSciences, Inc. | For profit | 1 | 1 | 1 | 2015 |
| Tianjin Cansino Biotechnology Inc | For profit | 1 | 0 | 1 | 2015 |
11 organizations
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