calcium propionate

Small moleculeexperimental

Calcium propionate (E282) is a preservative, antimould and antirope agent. Calcium propionate has been widely used as a preservative in bakery and in bread. The addition of 0.3 % calcium propionate prolonged the shelf-life of salt reduced bread to 10-12 days. It is sometimes not carefully used, or a high concentration is added to preserve products. High consumption of calcium propionate can lead to several health problems. Calcium propionate is used to prevent milk fever in cows and as a feed supplement. It is considered to be safe and effective treatment given for one or two days to prevent milk fever and/or to support treatment of milk fever. Calcium propionate is generally recognized as safe by FDA when used in accordance with good manufacturing or feeding practice. — NCATS

Clinical trial activity

5 trials · 6 clinical orgs · 0 marketing orgs

Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
0

Earliest trial started Aug 1, 2013 (NCT01889446)

Timeline

2010s

  1. Jan 1, 2017

    Earliest Phase 2 Sponsor(trial)

Indications

Mechanism of action

Chemistry & pharmacology

Loading structure…

SMILES

[Ca++].CCC([O-])=O.CCC([O-])=O
Mol. weight
186.219 g/mol

Oral

No

Parenteral

No

Topical

No

Sources

Also known as

  • calcium propionate
  • calcium propionate

Clinical trials

NCT IDPhaseStart dateSponsor(s)
NCT04788680N/AMar 31, 2021University of Vienna
NCT04236713N/AJan 21, 2020McMaster University
NCT04019951N/AJul 31, 2019DSM, Glycemic Index Laboratories, Inc
NCT03590496Phase 2Nov 21, 2017Humboldt University
NCT01889446N/AAug 1, 2013Harvard University
Showing 5 of 5 trials
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Organizations

Research & Development (6)

OrganizationOrg typeTrialsAs lead sponsorPhasesEarliest year
DSMFor profit1112019
Glycemic Index Laboratories, IncFor profit1012019
Harvard UniversityAcademic/Hospital1112013
Humboldt UniversityAcademic/Hospital1112017
McMaster UniversityAcademic/Hospital1112020
University of ViennaAcademic/Hospital1112021
6 organizations
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