autologous platelets
Cell therapyexperimental
Clinical trial activity
24 trials · 50 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
10
Phase 3
4
Phase 4
4
Earliest trial started Jul 1, 2003 (NCT00074763)
Timeline
Indications
Approved for
Studied for
- Acute-On-Chronic Liver Failure · Phase 4
- Blood Platelet Disorders · Phase 1/Phase 2
- Blood Platelets · Phase 2/Phase 3
- Blood Transfusion · Phase 2
- Cardiopulmonary Bypass · Phase 2/Phase 3
- Drug-Related Side Effects and Adverse Reactions · Phase 4
- Dupuytren Contracture · Phase 2/Phase 3
- Extracorporeal Membrane Oxygenation · Phase 4
- General Surgery · Phase 4
- Healthy Volunteers · Phase 2
- Heart Defects, Congenital · Phase 2
- Hematopoietic Stem Cell Transplantation · Phase 2
- Hemorrhage · Phase 4
- Infections · Phase 3
- Leukemia · Phase 3
- Leukemia, Biphenotypic, Acute · Phase 2
- Leukemia, Lymphocytic, Chronic, B-Cell · Phase 2
- Leukemia, Myelogenous, Chronic, BCR-ABL Positive · Phase 2
- Leukemia, Myeloid, Acute · Phase 2
- Lymphoma · Phase 3
- Lymphoma, Non-Hodgkin · Phase 2
- Myelodysplastic Syndromes · Phase 2
- Neutropenia · Phase 2
- Platelet Aggregation Inhibitors · Phase 1/Phase 2
- Precursor Cell Lymphoblastic Leukemia-Lymphoma · Phase 2
- Primary Myelofibrosis · Phase 2
- Thoracic Surgery · Phase 2/Phase 3
- Thrombocytopenia · Phase 4
- Thromboembolism · Phase 4
- Venous Thromboembolism · Phase 2
- Wounds and Injuries · Phase 3
Mechanism of action
- PlateletTissue restoration
tissue restoration - platelet
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- autologous platelets
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07064954 | Phase 2/Phase 3 (Phase 3) | Sep 1, 2025 | University of Toronto |
| NCT05796557 | Phase 4 | Nov 13, 2023 | Columbia University, Cornell University, Duke University, Emory University, Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), University of Iowa, University of Rochester, University of Utah, University of Wisconsin, Virginia Commonwealth University, Yale University |
| NCT06095648 | N/A | Oct 28, 2023 | Health Research Board, Ireland, Irish Blood Transfusion Service, National Maternity Hospital, Ireland, National University of Ireland |
| NCT05293106 | Phase 4 | Jul 5, 2022 | Cornell University |
| NCT04915287 | Phase 4 | Jun 6, 2021 | People's Liberation Army of China |
| NCT05111028 | Phase 1/Phase 2 (Phase 2) | Nov 20, 2020 | Bloodworks Northwest, Department of Defense |
| NCT06535360 | Phase 4 | Sep 1, 2020 | University of Maryland |
| NCT03968484 | N/A | Aug 1, 2019 | University of Tuebingen |
| NCT03712618 | Phase 2 | Jun 10, 2019 | National Institutes of Health (NIH) |
| NCT04564651 | N/A | May 1, 2019 | Southern Medical University |
| NCT03787927 | Phase 1/Phase 2 (Phase 2) | Dec 3, 2018 | Bloodworks Northwest, National Blood Foundation |
| NCT03561909 | N/A | Apr 17, 2018 | Fraunhofer, Fraunhofer-Institute of Toxicology and Experimental Medicine, German Red Cross, Larix A/S, Prophylix Pharma AS |
| NCT04807621 | Phase 2 | Mar 14, 2018 | University of Gothenburg |
| NCT03195010 | Phase 2 | Jun 9, 2017 | National Cancer Institute (NCI), University of Washington |
| NCT03090919 | N/A | Jan 3, 2017 | University of Kentucky |
| NCT02653443 | Phase 2 | Dec 31, 2015 | Cerus Corporation |
| NCT01615146 | N/A | Jun 30, 2012 | Canadian Blood Services, Canadian Institutes of Health Research (CIHR), University of Ottawa |
| NCT01248351 | Phase 2 | Nov 1, 2010 | CSL Behring, Medical University of Graz, Novo Nordisk |
| NCT00937053 | Phase 2 | Jun 30, 2009 | St. Justine's Hospital |
| NCT00672672 | Phase 3 | Feb 1, 2009 | University of Nebraska |
Showing 20 of 24 trials
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Organizations
Research & Development (50)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Bloodworks Northwest | Academic/Hospital | 2 | 2 | 1 | 2018 |
| Cornell University | Academic/Hospital | 2 | 1 | 1 | 2022 |
| Aix-University of Marseille | Academic/Hospital | 1 | 0 | 1 | 2007 |
| Canadian Blood Services | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Canadian Institutes of Health Research (CIHR) | Academic/Hospital | 1 | 0 | 1 | 2012 |
| Cerus Corporation | For profit | 1 | 1 | 1 | 2015 |
| Columbia University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| CSL Behring | For profit | 1 | 0 | 1 | 2010 |
| Department of Defense | Government | 1 | 0 | 1 | 2020 |
| Duke University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Emory University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Fraunhofer | For profit | 1 | 0 | 1 | 2018 |
| Fraunhofer-Institute of Toxicology and Experimental Medicine | Academic/Hospital | 1 | 0 | 1 | 2018 |
| German Red Cross | Academic/Hospital | 1 | 0 | 1 | 2018 |
| Ghent University | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Health Research Board, Ireland | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Irish Blood Transfusion Service | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Johns Hopkins University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Johnson and Johnson | For profit | 1 | 0 | 1 | 2008 |
| Larix A/S | For profit | 1 | 0 | 1 | 2018 |
50 organizations
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