autologous dendritic cells electroporated with wt1 mrna
Vaccineexperimental
Clinical trial activity
5 trials · 7 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
3
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2009 (NCT00929019)
Timeline
Indications
Mechanism of action
- Tumor antigensImmunity, active
immunity, active - tumor antigens
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- autologous dendritic cells electroporated with mrna
- autologous dendritic cells electroporated with wt1 mrna
- wt1 mrna loaded autologous dendritic cell
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT03908671 | N/A | May 31, 2019 | Stemirna Therapeutics, Zhengzhou University |
| NCT03468244 | N/A | May 1, 2018 | Changhai Hospital, Stemirna Therapeutics |
| NCT03083054 | Phase 1/Phase 2 (Phase 2) | Aug 1, 2016 | University of Campinas |
| NCT00965224 | Phase 2 | Jan 1, 2010 | University of Antwerp |
| NCT00929019 | Phase 1/Phase 2 (Phase 2) | Jun 1, 2009 | Radboud University, Rotterdam Eye Hospital |
Showing 5 of 5 trials
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Organizations
Research & Development (7)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Stemirna Therapeutics | For profit | 2 | 1 | 1 | 2018 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2018 |
| Radboud University | Academic/Hospital | 1 | 1 | 1 | 2009 |
| Rotterdam Eye Hospital | Academic/Hospital | 1 | 0 | 1 | 2009 |
| University of Antwerp | Academic/Hospital | 1 | 1 | 1 | 2010 |
| University of Campinas | Academic/Hospital | 1 | 1 | 1 | 2016 |
| Zhengzhou University | Academic/Hospital | 1 | 0 | 1 | 2019 |
7 organizations
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