cea car-t cells
Cell therapyexperimental
Clinical trial activity
25 trials · 19 clinical orgs · 0 marketing orgs
Phase 1
24
Phase 2
4
Phase 3
1
Phase 4
0
Earliest trial started Dec 1, 2014 (NCT02349724)
Timeline
Indications
Studied for
- Bile Duct Neoplasms · Phase 1
- Breast Neoplasms · Phase 1/Phase 2
- Carcinoembryonic Antigen · Phase 1
- Carcinoma · Phase 1
- Carcinoma, Hepatocellular · Phase 1/Phase 2
- Carcinoma, Non-Small-Cell Lung · Phase 1
- Cholangiocarcinoma · Phase 1
- Colonic Neoplasms · Phase 1/Phase 2
- Colorectal Neoplasms · Phase 1/Phase 2
- Esophageal Neoplasms · Phase 1/Phase 2
- Hamartoma · Phase 1
- Liver Neoplasms · Phase 1/Phase 2
- Lung Neoplasms · Phase 1/Phase 2
- Neoplasm Metastasis · Phase 1
- Neoplasms · Phase 1/Phase 2
- Pancreatic Neoplasms · Phase 2/Phase 3
- Peritoneal Neoplasms · Phase 1
- Rectal Neoplasms · Phase 1/Phase 2
- Stomach Neoplasms · Phase 1/Phase 2
Mechanism of action
- Carcinoembryonic antigen-related cell adhesion molecule 5Immunity, passive
CEACAM5 immunity, passive
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Also known as
- anti-cea car-t cells
- cea car-t cell
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT07247396 | Phase 1 | Nov 3, 2025 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT07250386 | Phase 1 | Oct 13, 2025 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT07179692 | Phase 1 | Sep 12, 2025 | Chongqing Precision Biotech Co., Ltd, People's Liberation Army of China |
| NCT06992583 | Phase 1 | May 8, 2025 | Chongqing Precision Biotech Co., Ltd |
| NCT06945523 | Phase 1 | Apr 28, 2025 | Chongqing Precision Biotech Co., Ltd |
| NCT06903117 | Phase 1 | Mar 24, 2025 | Chongqing Precision Biotech Co., Ltd |
| NCT06768151 | Phase 1 | Dec 12, 2024 | Chongqing Precision Biotech Co., Ltd |
| NCT06821048 | Phase 1 | Jul 24, 2024 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT06126406 | Phase 1 | Nov 6, 2023 | Chongqing Precision Biotech Co., Ltd, Wannan Medical College |
| NCT06010862 | Phase 1 | Sep 30, 2023 | Chongqing Precision Biotech Co., Ltd, Nanchang University |
| NCT06006390 | Phase 1/Phase 2 (Phase 2) | Sep 7, 2023 | Chongqing Precision Biotech Co., Ltd, Shanxi Bethune Hospital |
| NCT06013111 | Phase 1 | Sep 1, 2023 | China Medical University, Government of China |
| NCT06043466 | Phase 1 | Aug 11, 2023 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT05240950 | Phase 1 | Aug 25, 2022 | Changhai Hospital |
| NCT05538195 | Phase 1/Phase 2 (Phase 2) | Jun 7, 2022 | Chongqing Precision Biotech Co., Ltd, Henan Medical University |
| NCT05396300 | Phase 1 | May 25, 2022 | Chongqing Precision Biotech Co., Ltd, Zhejiang University |
| NCT05415475 | Phase 1 | Sep 10, 2021 | Chongqing Precision Biotech Co., Ltd, Shandong University |
| NCT04513431 | Early Phase 1 (Phase 1) | Aug 30, 2020 | HuaDao (Shanghai) Biomedical Co., Ltd., Jiao Tong University |
| NCT04348643 | Phase 1/Phase 2 (Phase 2) | Apr 20, 2020 | Chongqing Precision Biotech Co., Ltd |
| NCT04037241 | Phase 2/Phase 3 (Phase 3) | Nov 1, 2019 | Sorrento Therapeutics, Inc. |
Showing 20 of 25 trials
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Organizations
Research & Development (19)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Chongqing Precision Biotech Co., Ltd | For profit | 16 | 12 | 2 | 2020 |
| Zhejiang University | Academic/Hospital | 5 | 4 | 1 | 2022 |
| Boston University | Academic/Hospital | 3 | 2 | 1 | 2015 |
| People's Liberation Army of China | Government | 2 | 1 | 1 | 2014 |
| Sorrento Therapeutics, Inc. | For profit | 2 | 2 | 2 | 2018 |
| Changhai Hospital | Academic/Hospital | 1 | 1 | 1 | 2022 |
| China Medical University | Academic/Hospital | 1 | 1 | 1 | 2023 |
| Fudan University | Academic/Hospital | 1 | 0 | 1 | 2016 |
| Government of China | Government | 1 | 0 | 1 | 2023 |
| Henan Medical University | Academic/Hospital | 1 | 0 | 1 | 2022 |
| HuaDao (Shanghai) Biomedical Co., Ltd. | Academic/Hospital | 1 | 0 | 1 | 2020 |
| Jiao Tong University | Academic/Hospital | 1 | 1 | 1 | 2020 |
| Nanchang University | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Shandong University | Academic/Hospital | 1 | 0 | 1 | 2021 |
| Shanghai GeneChem Co., Ltd. | For profit | 1 | 1 | 1 | 2016 |
| Shanxi Bethune Hospital | Academic/Hospital | 1 | 0 | 1 | 2023 |
| Sirtex Medical | For profit | 1 | 0 | 1 | 2015 |
| University of Colorado, Denver | Academic/Hospital | 1 | 0 | 1 | 2017 |
| Wannan Medical College | Academic/Hospital | 1 | 0 | 1 | 2023 |
19 organizations
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