anatabine
Small moleculeexperimental
Anatabine (uh-nat-uh-been,-bin) is one of the minor alkaloids found in plants in the family Solanaceae, which includes the tobacco plant and tomato. Commercial tobacco plants typically produce alkaloids at levels between 2% and 4% of total dry weight, with nicotine accounting for about 90% of the total alkaloid content, and the related compounds anatabine, nornicotine, and anabasine making up nearly all the rest. These compounds are thought to be biologically active, and part of plants' natural defense system against insects. — Wikipedia
Clinical trial activity
5 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
0
Earliest trial started May 1, 2011 (NCT01607619)
Timeline
Indications
Mechanism of action
STAT3 inhibitor
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaAnatabine ↗
Also known as
- anatabine
- anatabine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT02432313 | Phase 1 | Jan 1, 2015 | Quotient, Rock Creek Pharmaceuticals, Inc. |
| NCT01669876 | Phase 2 | Aug 1, 2012 | Rock Creek Pharmaceuticals, Inc., Roskamp Institute |
| NCT01551498 | Phase 2 | Mar 1, 2012 | Rock Creek Pharmaceuticals, Inc. |
| NCT01428310 | Phase 1 | Sep 1, 2011 | Rock Creek Pharmaceuticals, Inc. |
| NCT01607619 | N/A | May 1, 2011 | McLaren Greater Lansing, Roskamp Institute |
Showing 5 of 5 trials
Page 1 / 1
Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Rock Creek Pharmaceuticals, Inc. | For profit | 4 | 4 | 2 | 2011 |
| Roskamp Institute | Academic/Hospital | 2 | 1 | 2 | 2011 |
| McLaren Greater Lansing | Academic/Hospital | 1 | 0 | 1 | 2011 |
| Quotient | For profit | 1 | 0 | 1 | 2015 |
4 organizations
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