endoprotease
Biologicalexperimental
Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids, in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids. For this reason, endopeptidases cannot break down peptides into monomers, while exopeptidases can break down proteins into monomers. A particular case of endopeptidase is the oligopeptidase, whose substrates are oligopeptides instead of proteins. — Wikipedia
Clinical trial activity
3 trials · 4 clinical orgs · 0 marketing orgs
Phase 1
0
Phase 2
0
Phase 3
0
Phase 4
1
Earliest trial started Apr 1, 2011 (NCT01335503)
Timeline
No events for the selected filters.
Indications
Approved for
Studied for
Mechanism of action
- GlutenDEGRADER
Gluten degrader
Chemistry & pharmacology
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaEndopeptidase ↗
Also known as
- endoprotease
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04788797 | Phase 4 | Mar 17, 2021 | Dr. C. Bonorino Udaondo Gastroenterology Hospital |
| NCT02060864 | N/A | Apr 1, 2014 | DSM, Orebro University |
| NCT01335503 | N/A | Apr 1, 2011 | DSM, Maastricht University |
Showing 3 of 3 trials
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Organizations
Research & Development (4)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| DSM | For profit | 2 | 2 | 1 | 2011 |
| Dr. C. Bonorino Udaondo Gastroenterology Hospital | Academic/Hospital | 1 | 1 | 1 | 2021 |
| Maastricht University | Academic/Hospital | 1 | 0 | 1 | 2011 |
| Orebro University | Academic/Hospital | 1 | 0 | 1 | 2014 |
4 organizations
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