apocynin
Small moleculeexperimental
Apocynin, also known as acetovanillone, is a natural organic compound structurally related to vanillin. It has been isolated from a variety of plant sources and is being studied for its variety of pharmacological properties. — Wikipedia
Clinical trial activity
6 trials · 5 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Jun 1, 2008 (NCT00992667)
Timeline
Indications
Mechanism of action
- UnclearUnclear
Unclear unclear
Chemistry & pharmacology
Loading structure…
SMILES
COc1cc(C(C)=O)ccc1O- Mol. weight
- 166.18 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- Achiral Molecule
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaApocynin ↗
- ChEMBLCHEMBL346919 ↗
Also known as
- 4-hydroxy-3-methoxyacetophenone
- 4'-hydroxy-3'-methoxyacetophenone
- acetovanillone
- acetovanillone
- acetovanillone
- apocynin
- apocynin
- apocynin
- apocynin
- apocynine
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04657926 | Phase 2 | Sep 9, 2020 | AKL Research and Development, Nordic Bioscience |
| NCT03680404 | Phase 1 | Oct 1, 2018 | University of Texas, Arlington |
| NCT03680573 | Phase 1 | Jan 8, 2018 | University of Texas, Arlington |
| NCT03680638 | Phase 1 | Sep 7, 2016 | University of Texas, Arlington |
| NCT01402297 | Phase 1 | Oct 1, 2010 | Government of Poland, Medical University of Lodz |
| NCT00992667 | Phase 1 | Jun 1, 2008 | Government of Poland, Medical University of Lodz |
Showing 6 of 6 trials
Page 1 / 1
Organizations
Research & Development (5)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Texas, Arlington | Academic/Hospital | 3 | 3 | 1 | 2016 |
| Government of Poland | Government | 2 | 0 | 1 | 2008 |
| Medical University of Lodz | Academic/Hospital | 2 | 2 | 1 | 2008 |
| AKL Research and Development | For profit | 1 | 1 | 1 | 2020 |
| Nordic Bioscience | For profit | 1 | 0 | 1 | 2020 |
5 organizations
Page 1 / 1