lactisole
Small moleculeexperimental
Lactisole is the sodium salt and commonly supplied form of 2-(4-methoxyphenoxy)propionic acid, a natural carboxylic acid found in roasted coffee beans. Like gymnemic acid, it has the property of masking sweet flavors and is used for this purpose in the food industry. — Wikipedia
Clinical trial activity
10 trials · 10 clinical orgs · 0 marketing orgs
Phase 1
5
Phase 2
1
Phase 3
0
Phase 4
0
Earliest trial started Mar 31, 2008 (NCT00631293)
Timeline
2000s
- Jan 1, 2008
Earliest Phase 1 Sponsor(trial)
Indications
Mechanism of action
Chemistry & pharmacology
Loading structure…
SMILES
COc1ccc(OC(C)C(=O)O)cc1- Mol. weight
- 196.2 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- No
- Chirality
- Racemic Mixture
- Inorganic
- No
- Polymer
- No
Oral
No
Parenteral
No
Topical
No
Sources
- WikipediaLactisole ↗
- ChEMBLCHEMBL573448 ↗
Also known as
- lactisole
- lactisole
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT04991714 | Early Phase 1 (Phase 1) | Aug 5, 2021 | University of Vienna |
| NCT04027283 | N/A | Aug 1, 2019 | St. Claraspital Basel, University of Basel |
| NCT04058340 | N/A | Jul 30, 2019 | Medical University of Lodz |
| NCT03032640 | N/A | Jan 26, 2017 | Advent Health, Translational Research Institute for Metabolism and Diabetes, Florida |
| NCT01918566 | N/A | Mar 1, 2012 | University of Bern |
| NCT01304823 | Phase 1 | Jun 30, 2010 | University of Basel |
| NCT01121783 | N/A | May 31, 2010 | Northern Care Alliance NHS Foundation Trust, University of Manchester |
| NCT01302574 | Phase 1 | Jan 31, 2010 | University of Basel |
| NCT01088841 | Phase 1 | Apr 30, 2009 | University of Basel |
| NCT00631293 | Phase 1/Phase 2 (Phase 2) | Mar 31, 2008 | Ghent University |
Showing 10 of 10 trials
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Organizations
Research & Development (10)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| University of Basel | Academic/Hospital | 4 | 4 | 2 | 2009 |
| Advent Health | Academic/Hospital | 1 | 1 | 1 | 2017 |
| Ghent University | Academic/Hospital | 1 | 1 | 1 | 2008 |
| Medical University of Lodz | Academic/Hospital | 1 | 1 | 1 | 2019 |
| Northern Care Alliance NHS Foundation Trust | Academic/Hospital | 1 | 1 | 1 | 2010 |
| St. Claraspital Basel | Academic/Hospital | 1 | 0 | 1 | 2019 |
| Translational Research Institute for Metabolism and Diabetes, Florida | Academic/Hospital | 1 | 0 | 1 | 2017 |
| University of Bern | Academic/Hospital | 1 | 1 | 1 | 2012 |
| University of Manchester | Academic/Hospital | 1 | 0 | 1 | 2010 |
| University of Vienna | Academic/Hospital | 1 | 1 | 1 | 2021 |
10 organizations
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